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Rosuvastwtin with all statins, there is a concern of rhabdomyolysisRosuvastatun severe undesired side effect. Create Rosuvastatin tailored to your choices of job role, location and industry, Rosuvadtatin new matching jobs from top employers will be sent to you daily. You can also report them to the U. Atheroscler Suppl. Multum does not assume any responsibility for any aspect of healthcare administered with the aid of information Multum provides. Patients were then randomized to once-daily oral treatment with rosuvastatin 10 mg or atorvastatin 20 mg for 6 weeks. Am Heart J. The following medications may increase the serum concentrations of rosuvastatin: asunaprevir, clopidogrel, cobicistat, cyclosporine, daclatasvir, dasabuvir, dronedarone, elbasvir, eltrombopag, eluxadoline, fostamatinib, glecaprevir, pibrentasvir, grazoprevir, itraconazole, ledipasvir, letermovir, ombitasvir, paritaprevir, ritonavir, osimertinib, protease inhibitors, simeprevir, teriflunomide, velpatasvir, voxilaprevir. Pulse is owned by Cogora. Metrics details. To learn more about how we use your information, see our Privacy Policy. This dosage is not suitable for everyone. Common side effects include abdominal pain, nausea, headaches, and muscle pains. If the pain does not return after switching back to Lipitor, you can probably be sure that it was the Crestor that was the source of the pain. Namespaces Article Talk. As with many medications, alcohol may affect the drug absorption. For women, rosuvastatin may slightly increase the hormones released into your system from some contraceptive pills. I have always has concerns with use of statins in primary prevention. Only if symptoms suggest underlying hepatotoxicity during therapy, it may be beneficial to obtain these levels. Int J Clin Pract. This lowers your risk of heart and blood vessel disease. A: Crestor rosuvastatin is a synthetic lipid-lowering agent. And other side effects include, stomach upset, heartburn, constipation, bloating and gas. Most supplements have not been tested to find out if they interact with medicines, foods, or other herbs and supplements. Nevertheless, there has been some concern regarding the potential toxicity of rosuvastatin, particularly in terms of renal and muscle events [41]. Recent reports of statins causing diabetes and even Parkinson's should alert NICE and medical profession to possible future problems arising out of usage of statins. Writing in the BMJDr Sidney Wolfe — senior adviser to US pressure group Public Citizen — argues that although rosuvastatin is more effective at lowering cholesterol than other statins, there is only relatively weak evidence for its effects on long-term outcomes.

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I have no red for climbing stairs. You will find a full list in the extra's moisture magnet supplied Roauvastatin your red. The potential health of the other lipid-independent pleiotropic paintings of statins in the container of acute respiratory syndromes. The most common side effects with Crestor are small pain, stature and sore area. Every prostatitis has been made to worry that the calcium provided by on this page is huge, up-to-date, and tried, but no side is made to that mother. Q: When is the best time of day to take Crestor? Rosuvastatin According to drug information, Crestor rosuvastatin has reported adverse reactions of both myalgia and arthralgia. Teratogenic risk of statins in pregnancy. The most common Rosuvaetatin effects with Crestor are muscle pain, constipation and sore Rosuvastztin. The oral route can be taken with or without food, at any time of the day, and should be swallowed whole. Joseph Hall, RPh. Unwanted effects often improve as your body adjusts to the new medicine, but speak with your doctor or pharmacist if any of the following continue or become troublesome. Metrics details. Nursing also bears responsibility for monitoring for adverse reactions, helping assess therapeutic effectiveness, and offering counsel to the patient, as well as serving as a bridge between the pharmacist and other providers and the prescriber. The following drugs might increase your risk of muscle problems if you take them with Crestor, so it is important to work with your doctor before combining these:. FDA-approved to reduce elevated bad cholesterol as part of a regimen that includes diet. Reprints and Permissions. If it is the concentration of cholesterol which has become too high, it is called hypercholesterolaemia. Patients were then randomized to once-daily oral treatment with rosuvastatin 10 mg or atorvastatin 20 mg for 6 weeks. Rare less than 0. Avoid drinking alcohol. It is used to decrease low-density lipoprotein LDL levels bad cholesteroldecrease triglyceride levels and increase high-density lipoprotein HDL levels good cholesterol in the blood. Monitoring for the effect of the drug and dose adjustment is best accomplished via an interprofessional approach, although it is manageable by a single provider. Top of the page. Search term. StatPearls [Internet]. You may report them to the FDA. To access free multiple choice questions on this topic, click here. Could this be a result of the statins? It's believed that grapefruit products interfere with an enzyme the body uses to break down certain statins, such as Zocor simvastatin and Lipitor atorvastatin. Now the muscle aches have returned. No formal analysis of statistical significance was performed Rosuvastatih the safety and tolerability data. Aspartate aminotransferase ASTalanine aminotransferase ALTalkaline phosphatase, and total bilirubin levels Rosuvasttain not need to Rossuvastatin routinely. Using Crestor alone is not enough: You will also have to eat a healthy diet and make other lifestyle changes like exercising, RRosuvastatin smokingand maintaining a healthy Rosuvastati. Swallow rosuvastatin tablets whole with a Rosuvastatib of water. Crestor Interactions. The drug was billed as a "super-statin" during its clinical development; the claim was that it Rosuvastatij high potency and improved cholesterol reduction compared to rivals in the class. For the first 12 months on this medicine, you'll be offered some routine tests to make sure your liver is working normally. Rosuvastatin 10 mg increased HDL-C levels to a significantly greater extent than atorvastatin 20 mg mean change 6. Niaspan niacin extended-release is used along with diet and exercise in patients with high cholesterol to help raise the level of HDL cholesterol the "good cholesterol" in your blood. I have been taking Crestor 20 mg for more than 3 years. The study reported the benefits of switching to more cost-effective statins in terms of potential savings to the health service[ 39 ]. Dosage recommendations: Dosing is individualized based on the low-density lipoprotein LDL levels at baseline and the goal of therapy. It's best to stop taking rosuvastatin at least 3 months before you start trying for a baby. Frequency not reported : Acute renal failure [ Ref ]. Your doctor is best able to guide your treatment choices based on your specific circumstances. Make sure your doctor knows if you are Asian. There are also reports of patients having rhabdomyolysis breakdown of muscle while taking Crestor rosuvastatin. Follow carefully any lifestyle advice you have been given such as stopping smoking, avoiding drinking too much alcohol, eating a healthy diet and taking exercise. The Cochrane Database of Systematic Reviews. Health Technol Assess.
Active Ingredient: Rosuvastatin
Rosuvastatin is used for lowering high cholesterol and triglycerides in certain patients.
Other names for this medication:
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Analogs of Rosuvastatin:

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    Rosuvastatin is used for lowering high cholesterol and triglycerides in certain patients. It also increases high-density lipoprotein (HDL, "good") cholesterol levels. It is also used to slow atherosclerosis (narrowing of the arteries) in patients with high blood cholesterol levels. It is used along with an appropriate diet. Rosuvastatin is an HMG-CoA reductase inhibitor, also known as a "statin." It works by reducing the production of certain fatty substances in the body, including cholesterol.


    Use Rosuvastatin as directed by your doctor.

    • Take Rosuvastatin by mouth with or without food.
    • If you also take an antacid that has aluminum or magnesium in it, take it at least 2 hours after taking Rosuvastatin. Check with your doctor if you have any questions.
    • Continue to take Rosuvastatin even if you feel well. Do not miss any dose.
    • If you miss a dose of Rosuvastatin, take it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not take 2 doses at once.

    Ask your health care provider any questions you may have about how to use Rosuvastatin.


     Store Rosuvastatin at room temperature, between 68 and 77 degrees F (20 to 25 degrees C). Store away from heat, moisture, and light. Keep Rosuvastatin out of the reach of children and away from pets.

  • Do NOT use Rosuvastatin if:

    • you are allergic to any ingredient in Rosuvastatin
    • you have liver problems or unexplained abnormal liver function tests
    • you are pregnant or breast-feeding
    • you are taking itraconazole, mibefradil, or telithromycin.

    Contact your doctor or health care provider right away if any of these apply to you.

    Some medical conditions may interact with Rosuvastatin. Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:

    • if you are planning to become pregnant
    • if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement
    • if you have allergies to medicines, foods, or other substances
    • if you have low blood pressure, a serious infection, kidney problems, an underactive thyroid, diabetes, or a history of seizures
    • if you are dehydrated or have certain muscle problems (eg, pain, weakness); have increased creatine phosphokinase (CPK) blood levels; or have metabolism, hormonal, or electrolyte problems
    • if you are on dialysis
    • if you drink alcohol or have a history of liver problems or alcohol abuse
    • if you have had an organ transplant or have recently had major surgery or a serious injury.

    Some medicines may interact with Rosuvastatin. Tell your health care provider if you are taking any other medicines, especially any of the following:

    • Fibrates (eg, gemfibrozil, clofibrate), immunosuppressants (eg, cyclosporine), lopinavir/ritonavir, or niacin because they may increase the risk of muscle or kidney problems
    • Anticoagulants (eg, warfarin), cimetidine, ketoconazole, macrolide immunosuppressants (eg, tacrolimus), or spironolactone because the risk of their side effects may be increased by Rosuvastatin.

    This may not be a complete list of all interactions that may occur. Ask your health care provider if Rosuvastatin may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.

    Important safety information:

    • Rosuvastatin may cause dizziness. These effects may be worse if you take it with alcohol or certain medicines. Use Rosuvastatin with caution. Do not drive or perform other possible unsafe tasks until you know how you react to it.
    • Drinking alcohol daily or in large amounts may increase the risk of liver problems with Rosuvastatin. Check with your doctor before drinking alcohol while you are taking Rosuvastatin.
    • Follow the diet and exercise program given to you by your health care provider.
    • Tell your doctor or dentist that you take Rosuvastatin before you receive any medical or dental care, emergency care, or surgery.
    • Women who may become pregnant should use effective birth control while taking Rosuvastatin. Check with your doctor if you have questions about using birth control.
    • Do NOT take more than the recommended dose without checking with your doctor.
    • Report any unexplained muscle pain, tenderness, or weakness to your doctor right away, especially if you also have a fever or general body discomfort.
    • Lab tests, including blood cholesterol levels, liver function, kidney function, and creatine phosphokinase (CPK) blood levels, may be performed while you use Rosuvastatin. These tests may be used to monitor your condition or check for side effects. Be sure to keep all doctor and lab appointments.
    • Use Rosuvastatin with caution in Asian patients and elderly patients; they may be more sensitive to its effects, especially serious muscle problems (eg, muscle pain, tenderness, or weakness).
    • Rosuvastatin should be used with extreme caution in children; safety and effectiveness in children have not been confirmed.
    • Pregnancy and breast-feeding: Do not use Rosuvastatin if you are pregnant. It may cause harm to the fetus. Avoid becoming pregnant while you are taking it. If you think you may be pregnant, contact your doctor right away. It is not known if Rosuvastatin is found in breast milk. Do not breastfeed while taking Rosuvastatin.
  • All medicines may cause side effects, but many people have no, or minor, side effects.

    Check with your doctor if any of these most common side effects persist or become bothersome:

    Constipation; sore throat.

    Seek medical attention right away if any of these severe side effects occur:

    Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); chest pain; dark urine; joint pain; muscle pain, tenderness, or weakness (with or without fever or fatigue); pale stools; severe or persistent headache; stomach pain; swelling of the hands, ankles, or feet; yellowing of the eyes or skin.

    This is not a complete list of all side effects that may occur. If you have questions about side effects, contact your health care provider.