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Some medicines are Plquenil suitable for people with Plasuenil conditions, and sometimes a medicine may only be used if extra care is taken. While these medications contain the same active ingredient, the preparation of generic hydroxychloroquine can sometimes cause stomach irritation. Plaquenil is prescribed as a disease-modifier, in other words, to decrease pain, decrease swelling, and prevent joint damage and disability. The aforementioned rare side effect that affects vision hydroxychloroquine retinopathyPlaqusnil caught early, may improve after discontinuation of Plaquenil. After one to three months, people with rheumatoid arthritis usually have a good response. For instance, wide-angle field imaging needs to be used on Asian patients in addition to the smaller-field imaging used on Caucasian patients. The reason why we do that is because we want to try to pick up the earliest possible signs of toxicity. The daily safe maximum dose for eye toxicity can be computed from one's height and weight using this calculator. Retrieved 10 July By using this site you agree to our use of cookies. Based on new scientific evidence, which Marmor and Ronald B. All rights reserved. Anti-malarial medications may prevent activation of plasmacytoid dendritic cells, a component of the immune system that is responsible for making interferon. Give today. Plaquenil is generally well-tolerated, but side effects are possible. Toll-like receptor 9 TLR 9 recognizes DNA-containing immune complexes and leads to the production of interferon and causes the dendritic cells to mature and present antigen to T cellstherefore reducing anti-DNA auto-inflammatory process. The Journal of Rheumatology. Wallace, Daniel, MD. Unneeded medications should be disposed of in special ways to ensure that pets, children, and other people cannot consume them. Moreover, Poaquenil damage will continue to progress and worsen even if the Plaquenil is stopped. You should always take your anti-malarial medications with food to prevent stomach upset. Antiparasitics — antiprotozoal agents — Chromalveolate antiparasitics P January 10, Plauenil Follow-up exams every 6 months or, annually at the very least are also advised. Why is this medication prescribed? Cannon, Michael, MD. Before using Plaquenil, tell your doctor if you are allergic to any drugs, or if you have psoriasis, porphyria, liver disease, alcoholism, or glucosephosphate dehydrogenase GPD deficiency. This site complies with the HONcode standard for trustworthy health information: verify here. Keep all appointments with your doctor and the laboratory. Anti-malarial medications may prevent activation of plasmacytoid dendritic cells, a component of the immune system that is responsible for making interferon. Hydroxychloroquine Plaquenilchloroquine Aralenand quinacrine Atabrine are medications that were originally used to prevent or treat malaria. Ina novel mechanism was described wherein hydroxychloroquine inhibits stimulation of the toll-like receptor TLR 9 family receptors. Antimalarial quinolines Antirheumatics. Academy Store. Anti-malarial drugs may have additional health benefits for some people. It is used to prevent and treat acute attacks of malaria. British Medical Association. At the recommended dose, development of visual problems due to the medication is rare. Two patients had cumulative lifetime dosages g and 12 g, respectively well below what is considered the toxic threshold. Lupus Therapies Continue to Evolve. The AAO published dosing and screening recommendations for chloroquine and hydroxychloroquine inrevising previous recommendations published in Call Help Get more information. Damage to the retina, the light sensitive portion of the inner eye, can occur with long-term use of Plaquenil or chloroquine Aralen. Plaquenil is a slow-acting drug. What else should I know? You have already added this topic to your email alerts. Arthritis Res Ther. Certain people are more susceptible than others to potential vision problems with Plaquenil. However, hydroxycholorquine has been shown to be safe during pregnancy and breast feeding. Visual field tests take a long time to complete and can be difficult for patients. Instead, the best way to dispose of your medication is through a medicine take-back program. Toxicity from hydroxychloroquine may be seen in two distinct areas of the eye: the cornea and the macula. Article Sources. When lupus spreads to these organs, immunosuppressive medications are usually added to help minimize irreversible injury. Notify your eye doctor when you are on this medication so regular Plaquenip screening tests can be performed. Daily news summary. Subscribe to our newsletters. When treating lupus or arthritis, tell your doctor if your symptoms do not improve after 6 months of treatment. Plaquenil and your eyes A rare side effect of Plaquenil is damage to the eye's retina. A rare side effect of Plaquenil is damage to the eye's retina. Plaquenil Interactions. HCQ retinopathy is typically asymptomatic in patients who are in the early stages of the disease, according to a study published in the Indian Journal of Ophthalmology by Hemang K. For these reasons, before you start taking hydroxychloroquine it is important that your doctor or pharmacist knows:. Hydroxychloroquine is widely used in the treatment of post-Lyme arthritis. These are all autoimmune diseases. Hydroxychloroquine mg-GG, white, round. Academy Store. HCQ retinopathy is typically asymptomatic in patients who are in the early stages of the disease, according to a study published in the Indian Journal of Ophthalmology by Hemang K. Plaquenil can cause serious liver or heart problems, especially if you use certain medicines at the same time, including:. Kim In addition to dosage, long duration of HCQ usage can put patients at higher risk for developing retinal toxicity. If side effects do occur, they are usually minor and last only for a short period of time. Be extra careful about taking medicines that affect your blood cells or immune system, or that may be harmful to your liver when you are taking Plaquenil. However, during World War II it was also found that these medications were effective in treating the symptoms of lupus. Follow-up exams every 6 months or, annually at the very least are also advised. Swallow hydroxychloroquine tablets with a meal or a glass of milk. Thank you Your feedback has been sent. Asian patients tend to have toxicity that begins a little farther from the fovea compared with Caucasian patients, often at the arcade region, so a wide-field imaging test is needed, Toy said. Drug Class. Purpose: : Plaquenil hydroxychloroquine is a drug that has been used to treat rheumatoid arthritis, lupus, and other autoimmune disorders for over 50 years. While these medications contain the same active ingredient, the preparation of generic hydroxychloroquine can sometimes cause stomach irritation. Find an Ophthalmologist.
Plaquenil
Plaquenil
Active Ingredient: Hydroxychloroquine
Plaquenil (hydroxychloroquine) is used to treat or prevent malaria, a disease caused by parasites that enter the body through the bite of a mosquito. Plaquenil is also used to treat symptoms of rheumatoid arthritis and lupus erythematosus.

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  • INDICATIONS 

    Plaquenil (hydroxychloroquine) is indicated for the suppressive treatment and treatment of acute attacks of malaria. It is also indicated for the treatment of discoid and systemic lupus erythematosus, and rheumatoid arthritis.

    INSTRUCTIONS

    You should not use Plaquenil if you are allergic to hydroxychloroquine, or if you have a history of vision changes or damage to your retina caused by hydroxychloroquine or similar anti-malaria medications. Before using Plaquenil, tell your doctor if you are allergic to any drugs, or if you have psoriasis, porphyria, liver disease, alcoholism, or glucose-6-phosphate dehydrogenase (G-6-PD) deficiency.

    Take Plaquenil exactly as prescribed by your doctor. Do not take in larger or smaller amounts or for longer than recommended. Follow the directions on your prescription label.Take Plaquenil with a meal or a glass of milk, unless your doctor tells you otherwise. Plaquenil is sometimes given only once per week. Choose the same day each week to take this medication if you are on a weekly dosing schedule.

    DOSAGE 

    Consult a doctor concerning the required dosage. If you missed a dose take the missed dose as soon as you remember. Skip the missed dose if it is almost time for your next scheduled dose. Do not take extra medicine to make up the missed dose.

    STORAGE

    Dispense in a tight, light-resistant container. Store at room temperature up to 30° C (86° F).